BDBM636187 7-chloro-2-(4-((3,3-difluorocyclobutyl)(methyl)amino)cyclohexyl)-2,4-dimethyl-N-((6-methyl-4-(methylthio)-2-oxo-1,2-dihydropyridin-3-yl)methyl)benzo[d][1,3]dioxole-5-carboxamide ::US20230365541, Compound 35

SMILES CSc1cc(C)[nH]c(=O)c1CNC(=O)c1cc(Cl)c2OC(C)(Oc2c1C)C1CCC(CC1)N(C)C1CC(F)(F)C1

InChI Key InChIKey=XWZDYQZFOFOYSQ-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 636187   

TargetHistone-lysine N-methyltransferase EZH2(Human)
Haisco Pharmaceuticals

US Patent
LigandPNGBDBM636187(7-chloro-2-(4-((3,3-difluorocyclobutyl)(methyl)ami...)
Affinity DataIC50: 0.590nMAssay Description:The compounds were dissolved in DMSO, formulated into 10 mM solutions and serially diluted with DMSO to obtain 100-fold the final concentration. 200 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/12/2024
Entry Details
US Patent