BDBM636217 US20230365541, Compound 61, isomer 2

SMILES CSc1cc(C)[nH]c(=O)c1CNC(=O)c1cc(Cl)c2c(c1C)OC(C)([C@H]1CC[C@@H](NC3COC3)CC1)O2

InChI Key InChIKey=VVFAJWYHTJJBDS-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 636217   

TargetHistone-lysine N-methyltransferase EZH2(Human)
Haisco Pharmaceuticals

US Patent
LigandChemical structure of BindingDB Monomer ID 636217BDBM636217(US20230365541, Compound 61, isomer 2)
Affinity DataIC50: 0.25nMAssay Description:The compounds were dissolved in DMSO, formulated into 10 mM solutions and serially diluted with DMSO to obtain 100-fold the final concentration. 200 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/12/2024
Entry Details
US Patent