BDBM636327 US20230365546, Compound 110

SMILES C[C@H](NC(=O)c4cn(C)c5ccc(c3ccc2c(NC(=O)C1CC1)n[nH]c2c3)cc45)c6cccc(F)c6

InChI Key InChIKey=YNLNNOJZIGTICH-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 636327   

TargetReceptor-interacting serine/threonine-protein kinase 1(Human)
Sichuan University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 636327BDBM636327(US20230365546, Compound 110)
Affinity DataIC50: 16nMAssay Description:Inhibition of human RIPK1 (1 to 294 residues) preincubated for 15 mins followed by [gamma-33P]ATP addition and measured after 40 mins by scintillatio...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed