BDBM636529 US20230365558, Compound 48b

SMILES COc1cc2O[C@]3(CCOC3)C(=O)Nc2cc1C(=O)NC[C@H](O)CN1CCc2ccccc2C1

InChI Key InChIKey=PKXYXEOALQWFBV-BVZFJXPGSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 636529   

TargetProtein arginine N-methyltransferase 5(Human)
Medshine Discovery

US Patent
LigandPNGBDBM636529(US20230365558, Compound 48b)
Affinity DataIC50:  34.2nMAssay Description:Experimental objective: To test the inhibitory effect of compounds on PRMT5 enzyme activity. Experimental materials: PRMT5 enzyme. Experimental opera...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent