BDBM636537 US20230365583, Compound 6

SMILES COc1ccc(CCNc2ncnc3c4cccnc4sc23)cc1OC

InChI Key InChIKey=ZHLKRXBKTXFBLW-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 636537   

TargetUbiquitin carboxyl-terminal hydrolase 28(Human)
Dana-Farber Cancer Institute

US Patent
LigandPNGBDBM636537(US20230365583, Compound 6)
Affinity DataIC50: 5.50E+3nMAssay Description:USP28 (at 1 nM) was pre-incubated with different concentrations of inhibitors or DMSO as a control in 50 mM Tris pH 8, 50 mM NaCl, 0.002% Tween-20, 5...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/12/2024
Entry Details
US Patent