BDBM636544 US20230365583, Compound 13

SMILES CCCc1nc2sc3c(NCCc4ccc5OCCOc5c4)ncnc3c2c2CCCc12

InChI Key InChIKey=XBLALWPVEHJKEZ-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 636544   

TargetUbiquitin carboxyl-terminal hydrolase 28(Human)
Dana-Farber Cancer Institute

US Patent
LigandPNGBDBM636544(US20230365583, Compound 13)
Affinity DataIC50: 5.50E+3nMAssay Description:USP28 (at 1 nM) was pre-incubated with different concentrations of inhibitors or DMSO as a control in 50 mM Tris pH 8, 50 mM NaCl, 0.002% Tween-20, 5...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/12/2024
Entry Details
US Patent