BDBM636788 US20230382863, Compound I-8

SMILES Cc1c(Oc2cccc(c2)N=[S@](C)(N)=O)c(C(=O)NC2CC2)c(Nc2ccc(I)cc2F)n(C)c1=O

InChI Key InChIKey=XTLFLWJOTUBJJP-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 636788   

LigandChemical structure of BindingDB Monomer ID 636788BDBM636788(US20230382863, Compound I-8)
Affinity DataIC50: 100nMAssay Description:Table 3: Compound effects on binding affinity of MEK to BRAF or CRAF were followed by surface plasmon resonance (SPR) with single-cycle kinetic analy...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/19/2024
Entry Details
US Patent