BDBM636800 US20230382863, Compound I-60

SMILES CN1Cc2cc(Oc3c(C)c(=O)n(C)c(Nc4ccc(I)cc4F)c3C(=O)NC3CC3)ccc2NS1(=O)=O

InChI Key InChIKey=VRPJWZGZNNHACX-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 636800   

LigandChemical structure of BindingDB Monomer ID 636800BDBM636800(US20230382863, Compound I-60)
Affinity DataIC50: 550nMAssay Description:Table 3: Compound effects on binding affinity of MEK to BRAF or CRAF were followed by surface plasmon resonance (SPR) with single-cycle kinetic analy...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/19/2024
Entry Details
US Patent