BDBM636812 US20230382863, Compound I-38

SMILES CNS(=O)(=O)Nc1c(F)ccc(Oc2c(C)c(=O)n(C)c(Nc3ccc(I)cc3F)c2C(=O)NC2CC2)c1Cl

InChI Key InChIKey=FNJAIKIISVACTQ-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 636812   

LigandPNGBDBM636812(US20230382863, Compound I-38)
Affinity DataIC50: 100nMAssay Description:Table 3: Compound effects on binding affinity of MEK to BRAF or CRAF were followed by surface plasmon resonance (SPR) with single-cycle kinetic analy...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/19/2024
Entry Details
US Patent