BDBM636831 2-(2-chloro-6-fluoro-phenyl)-1- [(1S,3R)-6-fluoro-3-(hydroxymethyl)- 5-(3-hydroxy-3-methyl-butyl)-1- methyl-3,4-dihydro-1H-isoquinolin-2- yl]ethanone (Example 7)::US20230382869, Compound Table1.5

SMILES C[C@@H]1N([C@@H](CO)Cc2c1ccc(F)c2CCC(C)(C)O)C(=O)Cc1c(F)cccc1Cl

InChI Key InChIKey=PKAODZJKRSELRC-UHFFFAOYSA-N

Data  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 636831   

TargetD(1A) dopamine receptor(Human)
Eli Lilly

US Patent
LigandPNGBDBM636831(US20230382869, Compound Table1.5 | 2-(2-chloro-6-f...)
Affinity DataEC50:  10.2nMAssay Description:Test compound is serially diluted (1:2) with DMSO into assay plates (ProxiPlate-384 Plus, PerkinElmer) using acoustic dispensing (Labcyte) to provide...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/19/2024
Entry Details
US Patent