BDBM636912 N-(4-(4-(6-morpholinopyridin-2-yl)-1H- 1,2,3-triazol-1-yl)-3-(6-azaspiro[2.5]octan- 6-yl)phenyl)methanesulfonamide::US20230382889, Compound 54

SMILES CS(=O)(=O)Nc1ccc(c(c1)N1CCC2(CC2)CC1)-n1cc(nn1)-c1cccc(n1)N1CCOCC1

InChI Key InChIKey=GWDPJSXNIQEALR-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 636912   

TargetKinesin-like protein KIF18A(Human)
Volastra Therapeutics

US Patent
LigandPNGBDBM636912(US20230382889, Compound 54 | N-(4-(4-(6-morpholino...)
Affinity DataIC50: 8.30nMAssay Description:Test compounds were plated in a 3x dilution scheme in a 384-well plate. Assay buffer: 80 mM PIPES (pH 6.9), 1 mM MgCl2, 75 mM KCl, 1 mM EGTA, 1 mM DT...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/19/2024
Entry Details
US Patent