BDBM637017 N-(4-(4-(5-fluoro-6-(1,2-oxazinan-2- yl)pyridin-2-yl)-1H-1,2,3-triazol-1-yl)-3- (6-azaspiro[2.5]octan-6-yl)phenyl)-2- hydroxyethane-1-sulfonamide::US20230382889, Compound 154

SMILES OCCS(=O)(=O)Nc1ccc(c(c1)N1CCC2(CC2)CC1)-n1cc(nn1)-c1ccc(F)c(n1)N1CCCCO1

InChI Key InChIKey=XHCOWJHVJQPJKD-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 637017   

TargetKinesin-like protein KIF18A(Human)
Volastra Therapeutics

US Patent
LigandPNGBDBM637017(US20230382889, Compound 154 | N-(4-(4-(5-fluoro-6-...)
Affinity DataIC50: 7.10nMAssay Description:Test compounds were plated in a 3x dilution scheme in a 384-well plate. Assay buffer: 80 mM PIPES (pH 6.9), 1 mM MgCl2, 75 mM KCl, 1 mM EGTA, 1 mM DT...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/19/2024
Entry Details
US Patent