BDBM637066 WO2021067859, Compound I-18::WO2021067859, Compound I-20

SMILES ONC(=O)c1cnc(NC2(CC2)c2ccccn2)c(F)c1

InChI Key InChIKey=XTBOFUZNOWHZBU-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 637066   

TargetHistone deacetylase 6(Human)
Tenaya Therapeutics

US Patent
LigandPNGBDBM637066(WO2021067859, Compound I-18 | WO2021067859, Compou...)
Affinity DataIC50: 1.68nMAssay Description:Table 14: The compounds disclosed herein, in particular those of Formula (II), were synthesized according to methods disclosed in WO2021067859, which...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/19/2024
Entry Details
US Patent

TargetHistone deacetylase 6(Human)
Tenaya Therapeutics

US Patent
LigandPNGBDBM637066(WO2021067859, Compound I-18 | WO2021067859, Compou...)
Affinity DataIC50: 3.78nMAssay Description:Table 14: The compounds disclosed herein, in particular those of Formula (II), were synthesized according to methods disclosed in WO2021067859, which...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/19/2024
Entry Details
US Patent