BDBM637721 (R)-3-methyl-4-((1- (3-(1-methyl-1H- pyrazol-5- yl)phenoxy)propan-2- yl)oxy)benzonitrile::US11834430, Compound 39

SMILES C[C@H](COc1cccc(c1)-c1ccnn1C)Oc1ccc(cc1C)C#N

InChI Key InChIKey=IPMAECGFJWTQDT-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 637721   

TargetProtein-S-isoprenylcysteine O-methyltransferase(Human)
Agency For Science, Technology and Research

US Patent
LigandPNGBDBM637721(US11834430, Compound 39 | (R)-3-methyl-4-((1- (3-(...)
Affinity DataIC50: 4.70nMAssay Description:An ICMT enzymatic assay was developed using Promega's Methyltransferase-GloTMreagents. In the assay, ICMT catalyzes the methylation of the N-Acet...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/23/2024
Entry Details
US Patent