BDBM637988 US11834453, Example 92

SMILES Cc1cc(Nc2ncnc3cnc(nc23)N2C[C@H]3CCS(=O)(=O)C3C2)ccc1Oc1ccc2n(C)cnc2c1

InChI Key InChIKey=HGIBTNNIYZMLCH-BPNWFJGMSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 637988   

TargetReceptor tyrosine-protein kinase erbB-2(Human)
Array Biopharma

US Patent
LigandPNGBDBM637988(US11834453, Example 92)
Affinity DataIC50:  18.9nMAssay Description:The kinases were incubated with 250 nM TK-substrate biotin (CisBio, part of cat #62TK0PEC) at 1 mM ATP along with test compounds in a buffer consisti...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent

LigandPNGBDBM637988(US11834453, Example 92)
Affinity DataIC50:  10.7nMAssay Description:This synthesized DNA fragment was subsequently cloned into the baculovirus transfer vector, pAcSG2, between the NcoI and NotI sites. The resulting pl...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent