BDBM638066 US11834453, Example 169

SMILES Cc1cc(Nc2ncnc3cnc(nc23)N2CC[C@@H](O)C2)ccc1Oc1ccc2n(C)cnc2c1

InChI Key InChIKey=IPKYIOLALLWAQH-QGZVFWFLSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 638066   

TargetReceptor tyrosine-protein kinase erbB-2(Human)
Array Biopharma

US Patent
LigandPNGBDBM638066(US11834453, Example 169)
Affinity DataIC50:  11.2nMAssay Description:The kinases were incubated with 250 nM TK-substrate biotin (CisBio, part of cat #62TK0PEC) at 1 mM ATP along with test compounds in a buffer consisti...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent

LigandPNGBDBM638066(US11834453, Example 169)
Affinity DataIC50:  8.5nMAssay Description:This synthesized DNA fragment was subsequently cloned into the baculovirus transfer vector, pAcSG2, between the NcoI and NotI sites. The resulting pl...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent