BDBM638166 US11834453, Example 269
SMILES CCNc1ncc2ncnc(Nc3ccc(Oc4ccc5n(C)ccc5c4)c(C)c3)c2n1
InChI Key InChIKey=VOCXOCYXWFTDLA-UHFFFAOYSA-N
Data 2 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 2 hits for monomerid = 638166
Affinity DataIC50: 16.7nMAssay Description:The kinases were incubated with 250 nM TK-substrate biotin (CisBio, part of cat #62TK0PEC) at 1 mM ATP along with test compounds in a buffer consisti...More data for this Ligand-Target Pair
TargetReceptor tyrosine-protein kinase erbB-2 [676-775,'YVMA',776-1255](Human)
Array Biopharma
US Patent
Array Biopharma
US Patent
Affinity DataIC50: 12.1nMAssay Description:This synthesized DNA fragment was subsequently cloned into the baculovirus transfer vector, pAcSG2, between the NcoI and NotI sites. The resulting pl...More data for this Ligand-Target Pair