BDBM639154 US20230391736, Example S-217622
SMILES Cn1cc2cc(c(cc2n1)Cl)NC3=NC(=O)N(C(=O)N3Cc4cc(c(cc4F)F)F)Cc5ncn(n5)C
InChI Key InChIKey=QMPBBNUOBOFBFS-UHFFFAOYSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 13 hits for monomerid = 639154
Affinity DataIC50: 10nMAssay Description:In this test, an assay buffer consisting of 20 mM Tris-HCl, 100 mM sodium chloride, 1 mM EDTA, 10 mM DTT, and 0.01% BSA is used. For compounds with a...More data for this Ligand-Target Pair
Affinity DataIC50: 10nMAssay Description:Preparation of Assay Buffer:In this test, an assay buffer consisting of 20 mM Tris-Hl, 100 mM sodium chloride, 1 mM EDTA, 10 mM DTT, and 0.01% BSA is...More data for this Ligand-Target Pair
Affinity DataIC50: 18.9nMAssay Description:The fluorescence resonance energy transfer method reported in the literature is adopted (J in et al 0.2020. Structure of Mprofrom SARS-CoV-2 and disc...More data for this Ligand-Target Pair
Affinity DataIC50: 27nMAssay Description:The fluorescence resonance energy transfer method reported in the literature is adopted (J in et al 0.2020. Structure of Mprofrom SARS-CoV-2 and disc...More data for this Ligand-Target Pair
Affinity DataIC50: 33nMAssay Description:The inhibitory activity of the compounds against SARS-CoV-2 3CLpro was determined by fluorescence resonance energy transfer technique. A suitable amo...More data for this Ligand-Target Pair
Affinity DataIC50: 43nMAssay Description:The fluorescence resonance energy transfer method reported in the literature is adopted (J in et al 0.2020. Structure of Mprofrom SARS-CoV-2 and disc...More data for this Ligand-Target Pair
Affinity DataIC50: 44nMAssay Description:The fluorescence resonance energy transfer method reported in the literature is adopted (J in et al 0.2020. Structure of Mprofrom SARS-CoV-2 and disc...More data for this Ligand-Target Pair
Affinity DataIC50: 55nMAssay Description:The fluorescence resonance energy transfer method reported in the literature is adopted (J in et al 0.2020. Structure of Mprofrom SARS-CoV-2 and disc...More data for this Ligand-Target Pair
3D Structure (crystal)Affinity DataIC50: 134nMAssay Description:The fluorescence resonance energy transfer method reported in the literature is adopted (J in et al 0.2020. Structure of Mprofrom SARS-CoV-2 and disc...More data for this Ligand-Target Pair
Affinity DataIC50: 1.47E+3nMAssay Description:The fluorescence resonance energy transfer method reported in the literature is adopted (J in et al 0.2020. Structure of Mprofrom SARS-CoV-2 and disc...More data for this Ligand-Target Pair
Affinity DataIC50: 5.63E+3nMAssay Description:The fluorescence resonance energy transfer method reported in the literature is adopted (J in et al 0.2020. Structure of Mprofrom SARS-CoV-2 and disc...More data for this Ligand-Target Pair
Affinity DataIC50: 2.78E+4nMAssay Description:The fluorescence resonance energy transfer method reported in the literature is adopted (J in et al 0.2020. Structure of Mprofrom SARS-CoV-2 and disc...More data for this Ligand-Target Pair
Affinity DataIC50: 4.96E+6nMAssay Description:The fluorescence resonance energy transfer method reported in the literature is adopted (J in et al 0.2020. Structure of Mprofrom SARS-CoV-2 and disc...More data for this Ligand-Target Pair