BDBM639197 (S)-7-isopropoxy-4-((1-isopropylpiperidin-4-yl)ethynyl)-1-((5-oxopyrrolidin-2-yl)methoxy)isoquinoline-6-carboxamide::US20230391748, Compound I-19

SMILES CC(C)Oc1cc2c(OC[C@@H]3CCC(=O)N3)ncc(C#CC3CCN(CC3)C(C)C)c2cc1C(N)=O

InChI Key InChIKey=JNVFANLMGAYYBK-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 639197   

TargetInterleukin-1 receptor-associated kinase 4(Human)
Rigel Pharmaceuticals

US Patent
LigandPNGBDBM639197((S)-7-isopropoxy-4-((1-isopropylpiperidin-4-yl)eth...)
Affinity DataIC50: 6.70nMAssay Description:The ADP-Glo reagents were thawed at ambient temperature. The Kinase Detection Reagent was prepared by mixing kinase detection buffer with the lyophil...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/28/2024
Entry Details
US Patent