BDBM639198 4-(((1r,4S)-4-ethoxycyclohexyl)ethynyl)-7-isopropoxy-1-(((S)-5-oxopyrrolidin-2-yl)methoxy)isoquinoline-6-carboxamide::US20230391748, Compound I-20

SMILES CCO[C@H]1CC[C@@H](CC1)C#Cc1cnc(OC[C@@H]2CCC(=O)N2)c2cc(OC(C)C)c(cc12)C(N)=O

InChI Key InChIKey=HAKUFFXRYCPHIS-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 639198   

TargetInterleukin-1 receptor-associated kinase 4(Human)
Rigel Pharmaceuticals

US Patent
LigandPNGBDBM639198(4-(((1r,4S)-4-ethoxycyclohexyl)ethynyl)-7-isopropo...)
Affinity DataIC50: 7nMAssay Description:The ADP-Glo reagents were thawed at ambient temperature. The Kinase Detection Reagent was prepared by mixing kinase detection buffer with the lyophil...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/28/2024
Entry Details
US Patent