BDBM639220 4-(1-(cis-3-ethoxycyclobutyl)-1H-pyrazol-4-yl)-7-isopropoxy-1-(((S)-5-oxopyrrolidin-2-yl)methoxy)isoquinoline-6-carboxamide::US20230391748, Compound I-42

SMILES CCO[C@H]1C[C@H](C1)n1cc(cn1)-c1cnc(OC[C@@H]2CCC(=O)N2)c2cc(OC(C)C)c(cc12)C(N)=O

InChI Key InChIKey=MFIMLCQLFUVYKH-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 639220   

TargetInterleukin-1 receptor-associated kinase 4(Human)
Rigel Pharmaceuticals

US Patent
LigandPNGBDBM639220(4-(1-(cis-3-ethoxycyclobutyl)-1H-pyrazol-4-yl)-7-i...)
Affinity DataIC50: 6.40nMAssay Description:The ADP-Glo reagents were thawed at ambient temperature. The Kinase Detection Reagent was prepared by mixing kinase detection buffer with the lyophil...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/28/2024
Entry Details
US Patent