BDBM639326 Cis-7-(5-chloro-2-methoxy- phenyl)-5-fluoro-N-[3- (hydroxymethyl)cyclobutyl]be nzofuran-2-carboxamide::US20230391758, Compound 28

SMILES COc1ccc(Cl)cc1-c1cc(F)cc2cc(oc12)C(=O)N[C@@H]1C[C@H](CO)C1

InChI Key InChIKey=GDUCPNUJKARUOF-UHFFFAOYSA-N

Data  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 639326   

TargetCeramide glucosyltransferase(Human)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM639326(Cis-7-(5-chloro-2-methoxy- phenyl)-5-fluoro-N-[3- ...)
Affinity DataEC50:  0.600nMAssay Description:Using Promega's UDP-Glo™ Glycosyltransferase assay kit (Promega Corporation, Madison, WI, USA (Promega)), GCS activity was indirectly measur...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/28/2024
Entry Details
US Patent