BDBM639334 (R or S)-N-(4,4-difluoro-3- piperidyl)-7-(2- propoxyphenyl)benzofuran-2- carboxamide::US20230391758, Compound 36

SMILES CCCOc1ccccc1-c1cccc2cc(oc12)C(=O)NC1CNCCC1(F)F

InChI Key InChIKey=KROGVZZDTJRLAU-UHFFFAOYSA-N

Data  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 639334   

TargetCeramide glucosyltransferase(Human)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM639334((R or S)-N-(4,4-difluoro-3- piperidyl)-7-(2- propo...)
Affinity DataEC50:  1.40nMAssay Description:Using Promega's UDP-Glo™ Glycosyltransferase assay kit (Promega Corporation, Madison, WI, USA (Promega)), GCS activity was indirectly measur...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/28/2024
Entry Details
US Patent