BDBM639335 (R and S)-N-(quinuclidin-3- yl)-7-(1,3,5-trimethyl-1H- pyrazol-4-yl)benzofuran-2- carboxamide::US20230391758, Compound 37

SMILES Cc1nn(C)c(C)c1-c1cccc2cc(oc12)C(=O)NC1CN2CCC1CC2

InChI Key InChIKey=LNZGFVUXMGXRTF-UHFFFAOYSA-N

Data  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 639335   

TargetCeramide glucosyltransferase(Human)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM639335((R and S)-N-(quinuclidin-3- yl)-7-(1,3,5-trimethyl...)
Affinity DataEC50:  2.40nMAssay Description:Using Promega's UDP-Glo™ Glycosyltransferase assay kit (Promega Corporation, Madison, WI, USA (Promega)), GCS activity was indirectly measur...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/28/2024
Entry Details
US Patent