BDBM639364 US20230391768, Compound I-8

SMILES CCN1CCN(Cc2cc(cc(c2)C(F)(F)F)C(=O)Nc2ccc(C)c(c2)-c2ccc3nc(NC(=O)C4CC4)cn3c2)CC1

InChI Key InChIKey=NEJAELSVKJJYRJ-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 639364   

TargetTyrosine-protein kinase JAK2(Human)
Dana-Farber Cancer Institute

US Patent
LigandPNGBDBM639364(US20230391768, Compound I-8)
Affinity DataIC50: 824nMAssay Description:The JAK2 Z-Lyte biochemical assay was performed according to manufacturer's instructions (Life Technologies).More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/28/2024
Entry Details
US Patent