BDBM639395 N-{[6-({[(3,3- difluorocyclobutyl) methyl]amino} methyl)imidazo[1,2- a]pyridin-2-yl] methyl}-1H- pyrrolo[2,3- b]pyridine-5- carboxamide::US20230391770, Example 15

SMILES FC1(F)CC(CNCc2ccc3nc(CNC(=O)c4cnc5[nH]ccc5c4)cn3c2)C1

InChI Key InChIKey=NQQGYINIBRMHOU-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 639395   

LigandPNGBDBM639395(N-{[6-({[(3,3- difluorocyclobutyl) methyl]amino} m...)
Affinity DataIC50: 27.3nMAssay Description:The enzymatic assay was established to determine IC50 values for inhibition of RNA methyltransferase activity. The enzyme used was full-length his-ta...More data for this Ligand-Target Pair
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Date in BDB:
1/28/2024
Entry Details
US Patent