BDBM639404 ({2-[(4-{6- chloroimidazo[1,5- a]pyridin-8-yl}-1H- 1,2,3-triazol-1- yl)methyl]imidazo [1,2-a]pyridin-6- yl}methyl) (cyclobutylmethyl) amine::US20230391770, Example 24

SMILES Clc1cc(-c2cn(Cc3cn4cc(CNCC5CCC5)ccc4n3)nn2)c2cncn2c1

InChI Key InChIKey=VGBGMQGHYZIZHM-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 639404   

LigandPNGBDBM639404(({2-[(4-{6- chloroimidazo[1,5- a]pyridin-8-yl}-1H-...)
Affinity DataIC50: 6.10nMAssay Description:The enzymatic assay was established to determine IC50 values for inhibition of RNA methyltransferase activity. The enzyme used was full-length his-ta...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/28/2024
Entry Details
US Patent