BDBM639417 3-{1-[(6- {[({bicyclo[1.1.1] pentan-1- yl}methyl)amino] methyl}imidazo [1,2-a]pyridin-2- yl)methyl]-1H-1,2,3- triazol-4-yl}-5- methoxypyridine-2- carbonitrile::US20230391770, Example 37

SMILES COc1cnc(C#N)c(c1)-c1cn(Cc2cn3cc(CNCC45CC(C4)C5)ccc3n2)nn1

InChI Key InChIKey=WYAPJSKOQWSRRO-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 639417   

LigandPNGBDBM639417(3-{1-[(6- {[({bicyclo[1.1.1] pentan-1- yl}methyl)a...)
Affinity DataIC50: 11.2nMAssay Description:The enzymatic assay was established to determine IC50 values for inhibition of RNA methyltransferase activity. The enzyme used was full-length his-ta...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/28/2024
Entry Details
US Patent