BDBM640217 3-(5-(6-((2-(benzo[b]thiophen-5-yl)ethyl)amino)pyrimidin-4-yl)-3-ethoxythiophen-2-yl)-[1,2,4]oxadiazol-5-ol::US11839613, Example 340

SMILES CCOc1cc(sc1-c1noc(O)n1)-c1cc(NCCc2ccc3sccc3c2)ncn1

InChI Key InChIKey=PMXJZZCLJHTWBP-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 640217   

TargetProstaglandin E2 receptor EP4 subtype(Human)
Idorsia Pharmaceuticals

US Patent
LigandPNGBDBM640217(3-(5-(6-((2-(benzo[b]thiophen-5-yl)ethyl)amino)pyr...)
Affinity DataIC50: 11nMAssay Description:The BT549 cells (NCI/No. 0507282) are detached from culture dishes with a cell dissociation buffer (Invitrogen, 13151-014), and collected in growing ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/1/2024
Entry Details
US Patent

TargetProstaglandin E2 receptor EP2 subtype(Human)
Idorsia Pharmaceuticals

US Patent
LigandPNGBDBM640217(3-(5-(6-((2-(benzo[b]thiophen-5-yl)ethyl)amino)pyr...)
Affinity DataIC50: 104nMAssay Description:The SF295 cells (NCI/No. 0503170) are detached from culture dishes with a cell dissociation buffer (Invitrogen, 13151-014), and collected in growing ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/1/2024
Entry Details
US Patent