BDBM640305 (4-{6-[2-(7-Methoxy-5-methyl-2,3-dihydro-benzo[1,4]dioxin-6-yl)-ethylamino]- pyrimidin-4-yl}-2-trifluoromethoxy-phenyl)-acetic acid::US11839613, Example 428

SMILES COc1cc2OCCOc2c(C)c1CCNc1cc(ncn1)-c1ccc(CC(O)=O)c(OC(F)(F)F)c1

InChI Key InChIKey=HQRDCCBZVDPPDG-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 640305   

TargetProstaglandin E2 receptor EP2 subtype(Human)
Idorsia Pharmaceuticals

US Patent
LigandPNGBDBM640305((4-{6-[2-(7-Methoxy-5-methyl-2,3-dihydro-benzo[1,4...)
Affinity DataIC50: 7nMAssay Description:The SF295 cells (NCI/No. 0503170) are detached from culture dishes with a cell dissociation buffer (Invitrogen, 13151-014), and collected in growing ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/1/2024
Entry Details
US Patent

TargetProstaglandin E2 receptor EP4 subtype(Human)
Idorsia Pharmaceuticals

US Patent
LigandPNGBDBM640305((4-{6-[2-(7-Methoxy-5-methyl-2,3-dihydro-benzo[1,4...)
Affinity DataIC50: 50nMAssay Description:The BT549 cells (NCI/No. 0507282) are detached from culture dishes with a cell dissociation buffer (Invitrogen, 13151-014), and collected in growing ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/1/2024
Entry Details
US Patent