BDBM640781 US20230399319, Example 2-343

SMILES COC1COCCN(C1)S(=O)(=O)NC(=O)c1coc(Nc2cc(C(C)C)c(F)cc2C)n1

InChI Key InChIKey=DRRFJFQKLZJANH-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 640781   

TargetNACHT, LRR and PYD domains-containing protein 3(Human)
Japan Tobacco

US Patent
LigandPNGBDBM640781(US20230399319, Example 2-343)
Affinity DataIC50:  16nMAssay Description:The NLRP3 inflammasome inhibitory activity of test compounds were evaluated CM the basis of the inhibitory activity of the IL-1β, production in ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent