BDBM640939 US20230399342, Example 14

SMILES C[C@H]1CN(C(c2ccc(F)cc2)c2ccc(F)cc2)[C@H](CC#N)CN1c1nc2nncn2c2scnc12

InChI Key InChIKey=ZJWWHQTXONMGAH-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 640939   

TargetDiacylglycerol kinase alpha(Human)
Incyte

US Patent
LigandPNGBDBM640939(US20230399342, Example 14)
Affinity DataIC50: 20nMAssay Description:The DGKα and DGKξ biochemical reactions were performed using His-tagged human recombinant enzymes (Signal Chem, DGKα, #D21-1OBH; DGK&#...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/3/2024
Entry Details
US Patent

TargetDiacylglycerol kinase zeta(Human)
Incyte

US Patent
LigandPNGBDBM640939(US20230399342, Example 14)
Affinity DataIC50: 20nMAssay Description:The DGKα and DGKξ biochemical reactions were performed using His-tagged human recombinant enzymes (Signal Chem, DGKα, #D21-1OBH; DGK&#...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/3/2024
Entry Details
US Patent