BDBM640940 US20230399342, Example 15

SMILES C[C@H]1CN(C(c2ccc(F)cc2)c2ccc(F)cc2)[C@H](CC#N)CN1c1nc2nnc(C3CC3)n2c2scnc12

InChI Key InChIKey=FPDOHRGFFSXKPF-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 640940   

TargetDiacylglycerol kinase zeta(Human)
Incyte

US Patent
LigandPNGBDBM640940(US20230399342, Example 15)
Affinity DataIC50: 20nMAssay Description:The DGKα and DGKξ biochemical reactions were performed using His-tagged human recombinant enzymes (Signal Chem, DGKα, #D21-1OBH; DGK&#...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/3/2024
Entry Details
US Patent

TargetDiacylglycerol kinase alpha(Human)
Incyte

US Patent
LigandPNGBDBM640940(US20230399342, Example 15)
Affinity DataIC50: 110nMAssay Description:The DGKα and DGKξ biochemical reactions were performed using His-tagged human recombinant enzymes (Signal Chem, DGKα, #D21-1OBH; DGK&#...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/3/2024
Entry Details
US Patent