BDBM640942 US20230399342, Example 17

SMILES Fc1ccc(cc1)C(N1CCN(C[C@H]1CCC#N)c1nc2nncn2c2scnc12)c1ccc(F)cc1

InChI Key InChIKey=LOIVCBJKIGXUQD-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 640942   

TargetDiacylglycerol kinase alpha(Human)
Incyte

US Patent
LigandPNGBDBM640942(US20230399342, Example 17)
Affinity DataIC50: 20nMAssay Description:The DGKα and DGKξ biochemical reactions were performed using His-tagged human recombinant enzymes (Signal Chem, DGKα, #D21-1OBH; DGK&#...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/3/2024
Entry Details
US Patent

TargetDiacylglycerol kinase zeta(Human)
Incyte

US Patent
LigandPNGBDBM640942(US20230399342, Example 17)
Affinity DataIC50: 110nMAssay Description:The DGKα and DGKξ biochemical reactions were performed using His-tagged human recombinant enzymes (Signal Chem, DGKα, #D21-1OBH; DGK&#...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/3/2024
Entry Details
US Patent