BDBM642297 (5-amino-5-(1-(2-oxo-2-((2,4,5- trifluorobenzyl)amino)ethyl)-1H-tetrazol- 5-yl)pentyl)boronic acid::US11845767, Example 343

SMILES NC(CCCCB(O)O)c1nnnn1CC(=O)NCc1cc(F)c(F)cc1F

InChI Key InChIKey=JZHQTPGCVWDMPN-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 642297   

TargetArginase-1(Human)
Rijksuniversiteit Groningen

US Patent
LigandPNGBDBM642297((5-amino-5-(1-(2-oxo-2-((2,4,5- trifluorobenzyl)am...)
Affinity DataIC50: 15nMAssay Description:Inhibition of arginase I (ARG I) and arginase II (ARGG II) novel compounds is followed spectrophotometrically at 530 nm. The compound to be tested is...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/12/2024
Entry Details
US Patent