BDBM642359 US20230406840, Example 33

SMILES FC(F)(F)COc1ccc2nccc(C(=O)NCC(=O)N3[C@H]4C[C@H]4C[C@H]3C#N)c2c1

InChI Key InChIKey=HZNYSEWDRIXMGY-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 642359   

TargetProlyl endopeptidase FAP(Human)
Astrazeneca

US Patent
LigandPNGBDBM642359(US20230406840, Example 33)
Affinity DataIC50: 1.40nMAssay Description:Table 1A: Compounds were tested in a biochemical inhibition assay using hFAP enzyme at 0.24 nM FAC (Proteros, 38-760 (PR-0071)) and the substrate Ala...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/12/2024
Entry Details
US Patent