BDBM642972 US20240000767, Example 50::US20240000767, Example 51::US20240000767, Example 52::diamix-N-[(3,5-Difluoropyridin-2-yl)methyl]-2-[(3R)-3′-fluoro-3-methyl[1,4′-bipiperidin]-1′-yl]-1,3-thiazole-5-carboxamide

SMILES C[C@@H]1CCCN(C1)C1CCN(CC1F)c1ncc(s1)C(=O)NCc1ncc(F)cc1F

InChI Key InChIKey=KTHHJXFIHKRDIP-IMUUDWKMSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 642972   

TargetAlpha-2C adrenergic receptor(Human)
Bayer Aktiengesellschaft

US Patent
LigandPNGBDBM642972(US20240000767, Example 50 | US20240000767, Example...)
Affinity DataIC50:  73.5nMAssay Description:In Vitro Radioligand Binding Studies for Determination of the Dissociation Constants K1 at the Human Adrenoreceptor ADRA2C (Eurofins Panlabs Discover...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent


TargetAlpha-2C adrenergic receptor(Human)
Bayer Aktiengesellschaft

US Patent
LigandPNGBDBM642972(US20240000767, Example 50 | US20240000767, Example...)
Affinity DataIC50:  6.70nMAssay Description:In Vitro Radioligand Binding Studies for Determination of the Dissociation Constants K1 at the Human Adrenoreceptor ADRA2C (Eurofins Panlabs Discover...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent


TargetAlpha-2C adrenergic receptor(Human)
Bayer Aktiengesellschaft

US Patent
LigandPNGBDBM642972(US20240000767, Example 50 | US20240000767, Example...)
Affinity DataIC50:  150nMAssay Description:In Vitro Radioligand Binding Studies for Determination of the Dissociation Constants K1 at the Human Adrenoreceptor ADRA2C (Eurofins Panlabs Discover...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent