BDBM643175 US20240002377, Compound 4

SMILES OC[C@@H]1CC[C@H](CO1)Nc1c(cnc2[nH]cc(C(=O)c3ccc(Oc4ccccc4)cc3Cl)c12)C#N

InChI Key InChIKey=MEBKPAZFMTWDAX-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 643175   

TargetTyrosine-protein kinase BTK [C481S](Human)
Medshine Discovery

US Patent
LigandPNGBDBM643175(US20240002377, Compound 4)
Affinity DataIC50: 7.40nMAssay Description:1. The substrate was prepared in freshly prepared reaction buffer;2. The required cofactor was added to the above-mentioned substrate solution;3. The...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/28/2024
Entry Details
US Patent