BDBM643615 US20240002391, Compound 773

SMILES CCC(=O)N1CC[C@H](Nc2nc(OC)c3c(ccn3n2)-c2ccc(N=N)c(NCC(F)F)c2)[C@H](F)C1

InChI Key InChIKey=FWJSHKSGOIGKKL-UHFFFAOYSA-N

Data  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 643615   

TargetDual specificity tyrosine-phosphorylation-regulated kinase 1A(Human)
Biosplice Therapeutics

US Patent
LigandPNGBDBM643615(US20240002391, Compound 773)
Affinity DataEC50:  0.700nMAssay Description:Briefly, recombinant DYRK1A kinase, ATP and Ser/Thr peptide 18 were prepared in 1X Kinase buffer to final concentrations of 0.25 μg/mL, 15 μ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/28/2024
Entry Details
US Patent