BDBM643746 (4S)-8-bromo-7-chloro-6-(2,6-difluorophenyl)-4-ethyl-1-methyl-4H-[1,2,4]triazolo[4,3-a][1,4]benzodiazepine::US20240002393, Example 98

SMILES CC[C@@H]1N=C(c2c(F)cccc2F)c2c(Cl)c(Br)ccc2-n2c(C)nnc12

InChI Key InChIKey=GZDOCFURBKWCMZ-ZDUSSCGKSA-N

Data  4 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 643746   

LigandPNGBDBM643746((4S)-8-bromo-7-chloro-6-(2,6-difluorophenyl)-4-eth...)
Affinity DataKi:  4.40nMAssay Description:Table 1: Radioligand binding assays were carried out in a volume of 200 μL (96-well plates) which contained 100 μL of cell membranes, [3H]F...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent


LigandPNGBDBM643746((4S)-8-bromo-7-chloro-6-(2,6-difluorophenyl)-4-eth...)
Affinity DataKi:  57.6nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent


LigandPNGBDBM643746((4S)-8-bromo-7-chloro-6-(2,6-difluorophenyl)-4-eth...)
Affinity DataKi:  72nMAssay Description:Table 2: Electrophysiological experiments were performed using the Roboocyte instrument (MultiChannelSystems, Reutlingen, Germany) on days 3 to 5 aft...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent


LigandPNGBDBM643746((4S)-8-bromo-7-chloro-6-(2,6-difluorophenyl)-4-eth...)
Affinity DataKi:  1.47E+3nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent