BDBM644305 6-chloro-4-{4-[(2-hydroxy-5-methylphenyl)methyl]piperazin-1-yl}-1-methyl-2-oxo-1,2-dihydro-1,5-naphthyridine-3-carbonitrile::US11866430, Example 283

SMILES Cc1ccc(O)c(CN2CCN(CC2)c2c(C#N)c(=O)n(C)c3ccc(Cl)nc23)c1

InChI Key InChIKey=VIWGIHMKNPAZLS-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 644305   

TargetDiacylglycerol kinase zeta(Human)
Bristol-Myers Squibb

US Patent
LigandPNGBDBM644305(6-chloro-4-{4-[(2-hydroxy-5-methylphenyl)methyl]pi...)
Affinity DataIC50:  2.70E+4nMAssay Description:The compound inhibition studies were carried out as follows: 50 nL droplets of each test compound (top concentration 10 mM with 11 point, 3-fold dilu...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent


TargetDiacylglycerol kinase alpha(Human)
Bristol-Myers Squibb

US Patent
LigandPNGBDBM644305(6-chloro-4-{4-[(2-hydroxy-5-methylphenyl)methyl]pi...)
Affinity DataIC50:  120nMAssay Description:The compound inhibition studies were carried out as follows: 50 nL droplets of each test compound (top concentration 10 mM with 11 point, 3-fold dilu...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent