BDBM644443 5-((2-(4-((3- (hydroxymethyl) benzyl)amino) butoxy)ethyl) amino)benzo [c][2,6] naphthyridine- 8-carboxylic acid::US11866436, Example 37

SMILES OCc1cccc(CNCCCCOCCNc2nc3cc(ccc3c3cnccc23)C(O)=O)c1

InChI Key InChIKey=RPAZCKZIZMEAIN-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 644443   

TargetCasein kinase II subunit alpha [2-329](Human)
Cambridge Enterprise

US Patent
LigandPNGBDBM644443(US11866436, Example 37 | 5-((2-(4-((3- (hydroxymet...)
Affinity DataIC50: 0.436nMAssay Description:Final assay conditions comprised 0.2 nM CK2α, 50 μM peptide substrate (RRRADDSDDDDD), 15 μM ATP in 1× reaction buffer (40 mM Tris pH7....More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/2/2024
Entry Details
US Patent

TargetDual specificity protein kinase CLK2(Human)
Cambridge Enterprise

US Patent
LigandPNGBDBM644443(US11866436, Example 37 | 5-((2-(4-((3- (hydroxymet...)
Affinity DataIC50: 358nMAssay Description:The assay was conducted in the same way as described for CK2α, with final assay conditions comprising 20 nM CLK2 (Carna Biosciences-04-127), 50 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/2/2024
Entry Details
US Patent