BDBM644508 5-(3-(4-((3- (cyanomethyl)- 5-(trifluoro- methyl) benzyl)amino) butoxy) azetidin-1-yl) benzo[c][2,6] naphthyridine- 8-carboxylic acid::US11866436, Example 103

SMILES OC(=O)c1ccc2c(c1)nc(N1CC(C1)OCCCCNCc1cc(CC#N)cc(c1)C(F)(F)F)c1ccncc21

InChI Key InChIKey=OJAHYTKDTIYGRY-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 644508   

TargetCasein kinase II subunit alpha [2-329](Human)
Cambridge Enterprise

US Patent
LigandPNGBDBM644508(US11866436, Example 103 | 5-(3-(4-((3- (cyanomethy...)
Affinity DataIC50: 0.453nMAssay Description:Final assay conditions comprised 0.2 nM CK2α, 50 μM peptide substrate (RRRADDSDDDDD), 15 μM ATP in 1× reaction buffer (40 mM Tris pH7....More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/2/2024
Entry Details
US Patent

TargetDual specificity protein kinase CLK2(Human)
Cambridge Enterprise

US Patent
LigandPNGBDBM644508(US11866436, Example 103 | 5-(3-(4-((3- (cyanomethy...)
Affinity DataIC50: 232nMAssay Description:The assay was conducted in the same way as described for CK2α, with final assay conditions comprising 20 nM CLK2 (Carna Biosciences-04-127), 50 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/2/2024
Entry Details
US Patent