BDBM644907 US20240009175, Compound 14::US20240009175, Compound 15::[3-Ethyl-7-methoxy-6-(1H-tetrazol-5-yl)- imidazo[1,2-a]pyridin-2-yl]-phenyl-pyrimidin- 2-yl-methanol

SMILES CCc1c(nc2cc(OC)c(cn12)-c1nnn[nH]1)C(O)(c1ccccc1)c1ncccn1

InChI Key InChIKey=RVCQSLDUPUBMPN-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 644907   

TargetAcetyl-coenzyme A synthetase, cytoplasmic(Human)
Merck Patent

US Patent
LigandPNGBDBM644907([3-Ethyl-7-methoxy-6-(1H-tetrazol-5-yl)- imidazo[1...)
Affinity DataIC50: 55nMAssay Description:The assay was performed in Perkin Elmer 384 well white Proxiplates in a total volume of 8 μl. 1 nM (fc)C-term myc tagged ACSS2 (human, recombina...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/4/2024
Entry Details
US Patent

TargetAcetyl-coenzyme A synthetase, cytoplasmic(Human)
Merck Patent

US Patent
LigandPNGBDBM644907([3-Ethyl-7-methoxy-6-(1H-tetrazol-5-yl)- imidazo[1...)
Affinity DataIC50: 5.05E+3nMAssay Description:The assay was performed in Perkin Elmer 384 well white Proxiplates in a total volume of 8 μl. 1 nM (fc)C-term myc tagged ACSS2 (human, recombina...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/4/2024
Entry Details
US Patent