BDBM644925 US20240010634, Example 2::US20240010634, Example 4

SMILES COc1cc(ccc1Nc1ncc(C)c(Nc2cccc(NS(=O)(=O)C(C)(C)C)c2)n1)N1CCN(C)CC1

InChI Key InChIKey=WBFLCKMSJJYORG-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 644925   

TargetActivated CDC42 kinase 1(Human)
H. Lee Moffitt Cancer Center and Research Institute

US Patent
LigandPNGBDBM644925(US20240010634, Example 4 | US20240010634, Example ...)
Affinity DataIC50: 21.9nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/4/2024
Entry Details
US Patent

TargetActivated CDC42 kinase 1(Human)
H. Lee Moffitt Cancer Center and Research Institute

US Patent
LigandPNGBDBM644925(US20240010634, Example 4 | US20240010634, Example ...)
Affinity DataIC50: 34.5nMAssay Description:IC50s were determined using the in vitro HotSpot kinase assay (purified enzymes, 33P-ATP, an appropriate substrate and 1 μM ATP.).More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/4/2024
Entry Details
US Patent