BDBM645125 US11872217, Compound 1.005

SMILES CCOc1cc(O[C@H]2CCc3c2cccc3-c2cccc(COc3cc(COC)c(CN4CCC(CC4)OC(=O)C(C)C)cc3Cl)c2C)c(Cl)cc1CN1CCC(CC1)OC(=O)C(C)C

InChI Key InChIKey=UTKXFSLGKFUBFW-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 645125   

TargetProgrammed cell death 1 ligand 1(Human)
Chemocentryx

US Patent
LigandPNGBDBM645125(US11872217, Compound 1.005)
Affinity DataIC50: 5.05E+3nMAssay Description:96 Well plates were coated with 1 μg/mL of human PD-L1 (obtained from R&D) in PBS overnight at 4° C. The wells were then blocked with 2% BSA in ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/7/2024
Entry Details
US Patent