BDBM645351 Trans-2-(1-(phenylsulfonyl)indolin- 5-yl)cyclopropylamine::US11873292, Compound A1

SMILES NC1CC1c1ccc2N(CCc2c1)S(=O)(=O)c1ccccc1

InChI Key InChIKey=LAHXLAOPPUKCMA-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 645351   

TargetLysine-specific histone demethylase 1A(Human)
Shanghai Institute of Materia Medica

US Patent
LigandPNGBDBM645351(Trans-2-(1-(phenylsulfonyl)indolin- 5-yl)cycloprop...)
Affinity DataIC50: 1.79E+3nMAssay Description:Principle: LSD1 specifically removes the methylation modification at K4 lysine on H3 polypeptide substrate, making it a substrate without methylation...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/7/2024
Entry Details
US Patent