BDBM645356 US11873292, Compound A8::trans-N-(3-indolylmethylene)-2-(1- (phenylsulfonyl)indolin-5-yl) cyclopropylamine

SMILES O=S(=O)(N1CCc2cc(ccc12)C1CC1NCc1c[nH]c2ccccc12)c1ccccc1

InChI Key InChIKey=KNOCVPDEDDCICZ-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 645356   

TargetLysine-specific histone demethylase 1A(Human)
Shanghai Institute of Materia Medica

US Patent
LigandPNGBDBM645356(trans-N-(3-indolylmethylene)-2-(1- (phenylsulfonyl...)
Affinity DataIC50: 85.1nMAssay Description:Principle: LSD1 specifically removes the methylation modification at K4 lysine on H3 polypeptide substrate, making it a substrate without methylation...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/7/2024
Entry Details
US Patent

TargetAmine oxidase [flavin-containing] A(Human)
Shanghai Institute of Materia Medica

US Patent
LigandPNGBDBM645356(trans-N-(3-indolylmethylene)-2-(1- (phenylsulfonyl...)
Affinity DataIC50: 8.17E+4nMAssay Description:Principle: A specific luciferin derivative was used as a substrate. MAOA or MAOB can catalyze the conversion of substrate to luciferin methyl ester. ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/7/2024
Entry Details
US Patent

TargetAmine oxidase [flavin-containing] B(Human)
Shanghai Institute of Materia Medica

US Patent
LigandPNGBDBM645356(trans-N-(3-indolylmethylene)-2-(1- (phenylsulfonyl...)
Affinity DataIC50: 1.00E+5nMAssay Description:Principle: A specific luciferin derivative was used as a substrate. MAOA or MAOB can catalyze the conversion of substrate to luciferin methyl ester. ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/7/2024
Entry Details
US Patent