BDBM645367 Trans-tert-butyl 4-((4-((2-(1-(phenylsulfonyl))indolin- 5-yl)cyclopropylamino)methyl) piperidin-1-yl)methyl)benzoate::US11873292, Compound A25

SMILES CC(C)(C)OC(=O)c1ccc(CN2CCC(CNC3CC3c3ccc4N(CCc4c3)S(=O)(=O)c3ccccc3)CC2)cc1

InChI Key InChIKey=ZUHDLGGVEBMYLU-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 645367   

TargetLysine-specific histone demethylase 1A(Human)
Shanghai Institute of Materia Medica

US Patent
LigandPNGBDBM645367(Trans-tert-butyl 4-((4-((2-(1-(phenylsulfonyl))ind...)
Affinity DataIC50: 534nMAssay Description:Principle: LSD1 specifically removes the methylation modification at K4 lysine on H3 polypeptide substrate, making it a substrate without methylation...More data for this Ligand-Target Pair
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Date in BDB:
3/7/2024
Entry Details
US Patent