BDBM645375 Synthesis of (1R,3R)-3-[(7S)-2-[(R)-hydroxy(phenyl)methyl]-6-(methoxycarbonyl)-7-methyl-3H,6H,7H,8H,9H-imidazo[4,5-f]quinolin-3-yl]cyclohexane-1-carboxylic acid ::US20240016795, Compound 2

SMILES COC(=O)[C@@H]1CCC[C@H](C1)Nc1ccc2N([C@@H](C)CCc2c1NC(=O)[C@H](O)c1ccccc1)C(=O)OC

InChI Key InChIKey=HMHPLQATEMXHAU-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 645375   

TargetCREB-binding protein(Human)
Forma Therapeutics

US Patent
LigandPNGBDBM645375(US20240016795, Compound 2 | Synthesis of (1R,3R)-3...)
Affinity DataIC50: 10nMAssay Description:The potency and selectivity of CBP/P300 inhibitor compounds including Compound 1 were determined in biochemical time resolved fluorescence assays usi...More data for this Ligand-Target Pair
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Date in BDB:
3/12/2024
Entry Details
US Patent